Cell size and fat content of dietary-restricted Caenorhabditis elegans are regulated by ATX-2, an mTOR repressor

Dietary restriction (DR) is a metabolic intervention that extends the lifespan of multiple species, including yeast, flies, nematodes, rodents, and, arguably, rhesus monkeys and humans. Hallmarks of lifelong DR are reductions in body size, fecundity, and fat accumulation, as well as slower developme...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Bar, Daniel Z., Charar, Chayki, Dorfman, Jehudith, Yadid, Tam, Tafforeau, Lionel, Lafontaine, Denis L. J., Gruenbaum, Yosef
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2016
Pynciau:
PNAS Plus
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987808/
https://ncbi.nlm.nih.gov/pubmed/27457958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1512156113
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