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Global transcriptional changes caused by an EDMD mutation correlate to tissue specific disease phenotypes in C. elegans
There are numerous heritable diseases associated with mutations in the LMNA gene. Most of these laminopathic diseases, including several muscular dystrophies, are autosomal dominant and have tissue-specific phenotypes. Our previous studies have shown that the globally expressed Emery-Dreifuss muscul...
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| Опубликовано в: : | Nucleus |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5287205/ https://ncbi.nlm.nih.gov/pubmed/27673727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19491034.2016.1238999 |
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