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Measuring nucleus mechanics within a living multicellular organism: Physical decoupling and attenuated recovery rate are physiological protective mechanisms of the cell nucleus under high mechanical load

Nuclei within cells are constantly subjected to compressive, tensile, and shear forces, which regulate nucleoskeletal and cytoskeletal remodeling, activate signaling pathways, and direct cell-fate decisions. Multiple rheological methods have been adapted for characterizing the response to applied fo...

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Publicat a:Mol Biol Cell
Autors principals: Zuela-Sopilniak, Noam, Bar-Sela, Daniel, Charar, Chayki, Wintner, Oren, Gruenbaum, Yosef, Buxboim, Amnon
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7525816/
https://ncbi.nlm.nih.gov/pubmed/32583745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-01-0085
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