Structural Investigation of Park’s Nucleotide on Bacterial Translocase MraY: Discovery of Unexpected MraY Inhibitors

Systematic structural modifications of the muramic acid, peptide, and nucleotide moieties of Park’s nucleotide were performed to investigate the substrate specificity of B. subtilis MraY (MraY(BS)). It was found that the simplest analogue of Park’s nucleotide only bearing the first two amino acids,...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Chen, Kuo-Ting, Chen, Po-Ting, Lin, Cheng-Kun, Huang, Lin-Ya, Hu, Chia-Ming, Chang, Yi-Fan, Hsu, Hua-Ting, Cheng, Ting-Jen R., Wu, Ying-Ta, Cheng, Wei-Chieh
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987650/
https://ncbi.nlm.nih.gov/pubmed/27531195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31579
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker