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Lipid Requirements for the Enzymatic Activity of MraY Translocases and in Vitro Reconstitution of the Lipid II Synthesis Pathway

Screening of new compounds directed against key protein targets must continually keep pace with emerging antibiotic resistances. Although periplasmic enzymes of bacterial cell wall biosynthesis have been among the first drug targets, compounds directed against the membrane-integrated catalysts are h...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Henrich, Erik, Ma, Yi, Engels, Ina, Münch, Daniela, Otten, Christian, Schneider, Tanja, Henrichfreise, Beate, Sahl, Hans-Georg, Dötsch, Volker, Bernhard, Frank
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732233/
https://ncbi.nlm.nih.gov/pubmed/26620564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.664292
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