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Lipid Requirements for the Enzymatic Activity of MraY Translocases and in Vitro Reconstitution of the Lipid II Synthesis Pathway

Screening of new compounds directed against key protein targets must continually keep pace with emerging antibiotic resistances. Although periplasmic enzymes of bacterial cell wall biosynthesis have been among the first drug targets, compounds directed against the membrane-integrated catalysts are h...

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Pubblicato in:J Biol Chem
Autori principali: Henrich, Erik, Ma, Yi, Engels, Ina, Münch, Daniela, Otten, Christian, Schneider, Tanja, Henrichfreise, Beate, Sahl, Hans-Georg, Dötsch, Volker, Bernhard, Frank
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732233/
https://ncbi.nlm.nih.gov/pubmed/26620564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.664292
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