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Structural Investigation of Park’s Nucleotide on Bacterial Translocase MraY: Discovery of Unexpected MraY Inhibitors
Systematic structural modifications of the muramic acid, peptide, and nucleotide moieties of Park’s nucleotide were performed to investigate the substrate specificity of B. subtilis MraY (MraY(BS)). It was found that the simplest analogue of Park’s nucleotide only bearing the first two amino acids,...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4987650/ https://ncbi.nlm.nih.gov/pubmed/27531195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31579 |
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