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Preparative Scale Cell-free Production and Quality Optimization of MraY Homologues in Different Expression Modes

MraY translocase catalyzes the first committed membrane-bound step of bacterial peptidoglycan synthesis leading to the formation of lipid I. The essential membrane protein therefore has a high potential as target for drug screening approaches to develop antibiotics against Gram-positive as well as G...

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Detalhes bibliográficos
Main Authors: Ma, Yi, Münch, Daniela, Schneider, Tanja, Sahl, Hans-Georg, Bouhss, Ahmed, Ghoshdastider, Umesh, Wang, Jufang, Dötsch, Volker, Wang, Xiaoning, Bernhard, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234709/
https://ncbi.nlm.nih.gov/pubmed/21937437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.301085
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