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Utilizing complement evasion strategies to design complement-based antibacterial immunotherapeutics: lessons from the pathogenic Neisseriae

Novel therapies are urgently needed to combat the global threat of multidrug-resistant pathogens. Complement forms an important arm of innate defenses against infections. In physiological conditions, complement activation is tightly controlled by soluble and membrane-associated complement inhibitors...

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Библиографические подробности
Опубликовано в: :Immunobiology
Главные авторы: Ram, Sanjay, Shaughnessy, Jutamas, DeOliveira, Rosane B., Lewis, Lisa A., Gulati, Sunita, Rice, Peter A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987187/
https://ncbi.nlm.nih.gov/pubmed/27297292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imbio.2016.05.016
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