Genetic and Environmental Risk for Chronic Pain and the Contribution of Risk Variants for Major Depressive Disorder: A Family-Based Mixed-Model Analysis

BACKGROUND: Chronic pain is highly prevalent and a significant source of disability, yet its genetic and environmental risk factors are poorly understood. Its relationship with major depressive disorder (MDD) is of particular importance. We sought to test the contribution of genetic factors and shar...

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Publicado en:PLoS Med
Main Authors: McIntosh, Andrew M., Hall, Lynsey S., Zeng, Yanni, Adams, Mark J., Gibson, Jude, Wigmore, Eleanor, Hagenaars, Saskia P., Davies, Gail, Fernandez-Pujals, Ana Maria, Campbell, Archie I., Clarke, Toni-Kim, Hayward, Caroline, Haley, Chris S., Porteous, David J., Deary, Ian J., Smith, Daniel J., Nicholl, Barbara I., Hinds, David A., Jones, Amy V., Scollen, Serena, Meng, Weihua, Smith, Blair H., Hocking, Lynne J.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987025/
https://ncbi.nlm.nih.gov/pubmed/27529168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1002090
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