A Combined Pathway and Regional Heritability Analysis Indicates NETRIN1 Pathway Is Associated With Major Depressive Disorder

BACKGROUND: Genome-wide association studies (GWASs) of major depressive disorder (MDD) have identified few significant associations. Testing the aggregation of genetic variants, in particular biological pathways, may be more powerful. Regional heritability analysis can be used to detect genomic regi...

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Detalles Bibliográficos
Publicado en:Biol Psychiatry
Autores principales: Zeng, Yanni, Navarro, Pau, Fernandez-Pujals, Ana M., Hall, Lynsey S., Clarke, Toni-Kim, Thomson, Pippa A., Smith, Blair H., Hocking, Lynne J., Padmanabhan, Sandosh, Hayward, Caroline, MacIntyre, Donald J., Wray, Naomi R., Deary, Ian J., Porteous, David J., Haley, Chris S., McIntosh, Andrew M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2017
Materias:
Archival Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5262437/
https://ncbi.nlm.nih.gov/pubmed/27422368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2016.04.017
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