A Combined Pathway and Regional Heritability Analysis Indicates NETRIN1 Pathway Is Associated With Major Depressive Disorder

BACKGROUND: Genome-wide association studies (GWASs) of major depressive disorder (MDD) have identified few significant associations. Testing the aggregation of genetic variants, in particular biological pathways, may be more powerful. Regional heritability analysis can be used to detect genomic regi...

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Detalhes bibliográficos
Publicado no:Biol Psychiatry
Main Authors: Zeng, Yanni, Navarro, Pau, Fernandez-Pujals, Ana M., Hall, Lynsey S., Clarke, Toni-Kim, Thomson, Pippa A., Smith, Blair H., Hocking, Lynne J., Padmanabhan, Sandosh, Hayward, Caroline, MacIntyre, Donald J., Wray, Naomi R., Deary, Ian J., Porteous, David J., Haley, Chris S., McIntosh, Andrew M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Archival Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5262437/
https://ncbi.nlm.nih.gov/pubmed/27422368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2016.04.017
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