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Major depressive disorder and current psychological distress moderate the effect of polygenic risk for obesity on body mass index

Major depressive disorder (MDD) and obesity are frequently co-morbid and this correlation is partly due to genetic factors. Although specific genetic risk variants are associated with body mass index (BMI) and with larger effect sizes in depressed individuals, the genetic overlap and interaction wit...

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Detalhes bibliográficos
Publicado no:Transl Psychiatry
Main Authors: Clarke, T-K, Hall, L S, Fernandez-Pujals, A M, MacIntyre, D J, Thomson, P, Hayward, C, Smith, B H, Padmanabhan, S, Hocking, L J, Deary, I J, Porteous, D J, McIntosh, A M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490293/
https://ncbi.nlm.nih.gov/pubmed/26125155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2015.83
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