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Measuring Transmembrane Helix Interaction Strengths in Lipid Bilayers Using Steric Trapping

We have developed a method to measure strong transmembrane (TM) helix interaction affinities in lipid bilayers that are difficult to measure by traditional dilution methods. The method, called steric trapping, couples dissociation of biotinylated TM helices to a competitive binding by monovalent str...

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Bibliographic Details
Published in:Methods Mol Biol
Main Authors: Hong, Heedeok, Chang, Yu-Chu, Bowie, James U.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986992/
https://ncbi.nlm.nih.gov/pubmed/23975771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-62703-583-5_3
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