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Conditional knockdown of BCL2A1 reveals rate-limiting roles in BCR-dependent B-cell survival
Bcl2 family proteins control mitochondrial apoptosis and its members exert critical cell type and differentiation stage-specific functions, acting as barriers against autoimmunity or transformation. Anti-apoptotic Bcl2a1/Bfl1/A1 is frequently deregulated in different types of blood cancers in humans...
Shranjeno v:
| izdano v: | Cell Death Differ |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4986635/ https://ncbi.nlm.nih.gov/pubmed/26450454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.130 |
| Oznake: |
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