Protection against malaria in mice is induced by blood stage–arresting histamine-releasing factor (HRF)–deficient parasites

Although most vaccines against blood stage malaria in development today use subunit preparations, live attenuated parasites confer significantly broader and more lasting protection. In recent years, Plasmodium genetically attenuated parasites (GAPs) have been generated in rodent models that cause se...

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Vydáno v:J Exp Med
Hlavní autoři: Demarta-Gatsi, Claudia, Smith, Leanna, Thiberge, Sabine, Peronet, Roger, Commere, Pierre-Henri, Matondo, Mariette, Apetoh, Lionel, Bruhns, Pierre, Ménard, Robert, Mécheri, Salaheddine
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2016
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986535/
https://ncbi.nlm.nih.gov/pubmed/27432939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151976
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