Crystal structures of murine and human Histamine-Releasing Factor (HRF/TCTP) and a model for HRF dimerisation in mast cell activation

In allergic disease, mast cell activation is conventionally triggered by allergen-mediated cross-linking of receptor-bound IgE on the cell surface. In addition to its diverse range of intracellular roles in apoptosis, cell proliferation and cancer, Histamine-Releasing Factor (HRF) also activates mas...

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Udgivet i:Mol Immunol
Main Authors: Doré, Katy A., Kashiwakura, Jun-ichi, McDonnell, James M., Gould, Hannah J., Kawakami, Toshiaki, Sutton, Brian J., Davies, Anna M.
Format: Artigo
Sprog:Inglês
Udgivet: Pergamon Press 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966295/
https://ncbi.nlm.nih.gov/pubmed/29216544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2017.11.022
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