Disruption of Parasite hmgb2 Gene Attenuates Plasmodium berghei ANKA Pathogenicity

Eukaryotic high-mobility-group-box (HMGB) proteins are nuclear factors involved in chromatin remodeling and transcription regulation. When released into the extracellular milieu, HMGB1 acts as a proinflammatory cytokine that plays a central role in the pathogenesis of several immune-mediated inflamm...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Main Authors: Briquet, Sylvie, Lawson-Hogban, Nadou, Boisson, Bertrand, Soares, Miguel P., Péronet, Roger, Smith, Leanna, Ménard, Robert, Huerre, Michel, Mécheri, Salah, Vaquero, Catherine
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468538/
https://ncbi.nlm.nih.gov/pubmed/25916985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.03129-14
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