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Disruption of Parasite hmgb2 Gene Attenuates Plasmodium berghei ANKA Pathogenicity
Eukaryotic high-mobility-group-box (HMGB) proteins are nuclear factors involved in chromatin remodeling and transcription regulation. When released into the extracellular milieu, HMGB1 acts as a proinflammatory cytokine that plays a central role in the pathogenesis of several immune-mediated inflamm...
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| Publicat a: | Infect Immun |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4468538/ https://ncbi.nlm.nih.gov/pubmed/25916985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.03129-14 |
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