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Immunological memory to blood-stage malaria infection is controlled by the histamine releasing factor (HRF) of the parasite
While most subunit malaria vaccines provide only limited efficacy, pre-erythrocytic and erythrocytic genetically attenuated parasites (GAP) have been shown to confer complete sterilizing immunity. We recently generated a Plasmodium berghei (PbNK65) parasite that lacks a secreted factor, the histamin...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5567273/ https://ncbi.nlm.nih.gov/pubmed/28831137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09684-2 |
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