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Inhibition of histamine-mediated signaling confers significant protection against severe malaria in mouse models of disease
From the inoculation of Plasmodium sporozoites via Anopheles mosquito bites to the development of blood-stage parasites, a hallmark of the host response is an inflammatory reaction characterized by elevated histamine levels in the serum and tissues. Given the proinflammatory and immunosuppressive ac...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2271011/ https://ncbi.nlm.nih.gov/pubmed/18227221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071548 |
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