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Inhibition of histamine-mediated signaling confers significant protection against severe malaria in mouse models of disease

From the inoculation of Plasmodium sporozoites via Anopheles mosquito bites to the development of blood-stage parasites, a hallmark of the host response is an inflammatory reaction characterized by elevated histamine levels in the serum and tissues. Given the proinflammatory and immunosuppressive ac...

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Hlavní autoři: Beghdadi, Walid, Porcherie, Adeline, Schneider, Bradley S., Dubayle, David, Peronet, Roger, Huerre, Michel, Watanabe, Takeshi, Ohtsu, Hiroshi, Louis, Jacques, Mécheri, Salaheddine
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2271011/
https://ncbi.nlm.nih.gov/pubmed/18227221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20071548
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