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A general framework for meta-analyzing dependent studies with overlapping subjects in association mapping

Meta-analysis strategies have become critical to augment power of genome-wide association studies (GWAS). To reduce genotyping or sequencing cost, many studies today utilize shared controls, and these individuals can inadvertently overlap among multiple studies. If these overlapping individuals are...

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Bibliografiske detaljer
Udgivet i:Hum Mol Genet
Main Authors: Han, Buhm, Duong, Dat, Sul, Jae Hoon, de Bakker, Paul I. W., Eskin, Eleazar, Raychaudhuri, Soumya
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986332/
https://ncbi.nlm.nih.gov/pubmed/26908615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw049
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