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Using genomic annotations increases statistical power to detect eGenes

Motivation: Expression quantitative trait loci (eQTLs) are genetic variants that affect gene expression. In eQTL studies, one important task is to find eGenes or genes whose expressions are associated with at least one eQTL. The standard statistical method to determine whether a gene is an eGene req...

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Duong, Dat, Zou, Jennifer, Hormozdiari, Farhad, Sul, Jae Hoon, Ernst, Jason, Han, Buhm, Eskin, Eleazar
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908356/
https://ncbi.nlm.nih.gov/pubmed/27307612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw272
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