Using genomic annotations increases statistical power to detect eGenes

Motivation: Expression quantitative trait loci (eQTLs) are genetic variants that affect gene expression. In eQTL studies, one important task is to find eGenes or genes whose expressions are associated with at least one eQTL. The standard statistical method to determine whether a gene is an eGene req...

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Bibliographic Details
Published in:Bioinformatics
Main Authors: Duong, Dat, Zou, Jennifer, Hormozdiari, Farhad, Sul, Jae Hoon, Ernst, Jason, Han, Buhm, Eskin, Eleazar
Format: Artigo
Language:Inglês
Published: Oxford University Press 2016
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Ismb 2016 Proceedings July 8 to July 12, 2016, Orlando, Florida
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4908356/
https://ncbi.nlm.nih.gov/pubmed/27307612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw272
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