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An Optimal Weighted Aggregated Association Test for Identification of Rare Variants Involved in Common Diseases
The advent of next generation sequencing technologies allows one to discover nearly all rare variants in a genomic region of interest. This technological development increases the need for an effective statistical method for testing the aggregated effect of rare variants in a gene on disease suscept...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Genetics Society of America
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3120154/ https://ncbi.nlm.nih.gov/pubmed/21368279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.125070 |
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