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Rare Variant Association Testing Under Low-Coverage Sequencing

Deep sequencing technologies enable the study of the effects of rare variants in disease risk. While methods have been developed to increase statistical power for detection of such effects, detecting subtle associations requires studies with hundreds or thousands of individuals, which is prohibitive...

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Detalhes bibliográficos
Main Authors: Navon, Oron, Sul, Jae Hoon, Han, Buhm, Conde, Lucia, Bracci, Paige M., Riby, Jacques, Skibola, Christine F., Eskin, Eleazar, Halperin, Eran
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697979/
https://ncbi.nlm.nih.gov/pubmed/23636738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.150169
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