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Rare Variant Association Testing Under Low-Coverage Sequencing

Deep sequencing technologies enable the study of the effects of rare variants in disease risk. While methods have been developed to increase statistical power for detection of such effects, detecting subtle associations requires studies with hundreds or thousands of individuals, which is prohibitive...

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Autors principals: Navon, Oron, Sul, Jae Hoon, Han, Buhm, Conde, Lucia, Bracci, Paige M., Riby, Jacques, Skibola, Christine F., Eskin, Eleazar, Halperin, Eran
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697979/
https://ncbi.nlm.nih.gov/pubmed/23636738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.150169
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