A general framework for meta-analyzing dependent studies with overlapping subjects in association mapping

Meta-analysis strategies have become critical to augment power of genome-wide association studies (GWAS). To reduce genotyping or sequencing cost, many studies today utilize shared controls, and these individuals can inadvertently overlap among multiple studies. If these overlapping individuals are...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Hum Mol Genet
Prif Awduron: Han, Buhm, Duong, Dat, Sul, Jae Hoon, de Bakker, Paul I. W., Eskin, Eleazar, Raychaudhuri, Soumya
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2016
Pynciau:
Association Studies Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986332/
https://ncbi.nlm.nih.gov/pubmed/26908615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw049
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