Carregant...

S-nitrosylation of tissue-type plasminogen activator confers vasodilatory and antiplatelet properties on the enzyme.

Tissue-type plasminogen activator (t-PA) reacts upon exposure to endothelium-derived relaxing factor (EDRF) by way of the enzyme's single free sulfhydryl (Cys-83) to form a stable S-nitrosothiol protein adduct. S-nitrosylation endows t-PA with potent vasodilatory and antiplatelet properties tha...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Stamler, J S, Simon, D I, Jaraki, O, Osborne, J A, Francis, S, Mullins, M, Singel, D, Loscalzo, J
Format: Artigo
Idioma:Inglês
Publicat: 1992
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC49861/
https://ncbi.nlm.nih.gov/pubmed/1325644
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!