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Elevated Plasma α-Defensins (HNP1–3) Levels Correlated with IgA1 Glycosylation and Susceptibility to IgA Nephropathy

Aim. IgA nephropathy (IgAN) is the most common form of glomerulonephritis. Recent genome-wide association study (GWAS) suggested that DEFA locus (which encodes α-defensins) may play a key role in IgAN. Methods. The levels of α-defensins in 169 IgAN patients and 83 healthy controls were tested by ELI...

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Detalhes bibliográficos
Publicado no:Dis Markers
Main Authors: Qi, Yuan-yuan, Zhou, Xu-jie, Cheng, Fa-juan, Zhang, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985581/
https://ncbi.nlm.nih.gov/pubmed/27563166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/8123138
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