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Aberrantly Glycosylated IgA1 as a Factor in the Pathogenesis of IgA Nephropathy
Predominant or codominant immunoglobulin (Ig) A deposition in the glomerular mesangium characterizes IgA nephropathy (IgAN). Accumulated glomerular IgA is limited to the IgA1 subclass and usually galactose-deficient. This underglycosylated IgA may play an important role in the pathogenesis of IgAN....
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3034910/ https://ncbi.nlm.nih.gov/pubmed/21318178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/470803 |
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