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Two Polypyrimidine Tracts in Intron 4 of the Major Immediate Early Gene Are Critical for Gene Expression Switching from IE1 to IE2 and for Replication of Human Cytomegalovirus

The human cytomegalovirus (HCMV) major immediate early (MIE) gene is essential for viral replication. The most abundant products encoded by the MIE gene include IE1 and IE2. Genes of IE1 and IE2 share the MIE promoter (MIEP), the first 3 exons, and the first 2 introns. IE1 is expressed earlier than...

詳細記述

保存先:
書誌詳細
出版年:J Virol
主要な著者: Hou, Wangheng, Torres, Lilith, Cruz-Cosme, Ruth, Arroyo, Fernando, Irizarry, Luis, Luciano, Dalia, Márquez, Arturo, Rivera, Leslie L., Sala, Antonio L., Luo, Min-hua, Tang, Qiyi
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4984657/
https://ncbi.nlm.nih.gov/pubmed/27252533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00837-16
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