Expression of Human Cytomegalovirus IE1 Leads to Accumulation of Mono-SUMOylated PML That Is Protected from Degradation by Herpes Simplex Virus 1 ICP0

To countermeasure the host cellular intrinsic defense, cytomegalovirus (CMV) and herpes simplex viruses (HSV) have evolved the ability to disperse nuclear domain 10 (ND10, aka PML body). However, mechanisms underlying their action on ND10 differ. HSV infection produces ICP0, which degrades the ND10-...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Hou, Wangheng, Cruz-Cosme, Ruth, Wen, Fayuan, Ahn, Jin-Hyun, Reeves, Inez, Luo, Min-Hua, Tang, Qiyi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232464/
https://ncbi.nlm.nih.gov/pubmed/30258013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01452-18
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