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Ability of the Human Cytomegalovirus IE1 Protein To Modulate Sumoylation of PML Correlates with Its Functional Activities in Transcriptional Regulation and Infectivity in Cultured Fibroblast Cells

In one of the earliest events in human cytomegalovirus (HCMV)-infected cells, the major immediate-early (IE) protein IE1 initially targets to and then disrupts the nuclear structures known as PML oncogenic domains (PODs) or nuclear domain 10. Recent studies have suggested that modification of PML by...

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Detalhes bibliográficos
Main Authors: Lee, Hye-Ra, Kim, Do-Jun, Lee, Jang-Mi, Choi, Cheol Yong, Ahn, Byung-Yoon, Hayward, Gary S., Ahn, Jin-Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC416510/
https://ncbi.nlm.nih.gov/pubmed/15163746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.12.6527-6542.2004
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