Expression of Human Cytomegalovirus IE1 Leads to Accumulation of Mono-SUMOylated PML That Is Protected from Degradation by Herpes Simplex Virus 1 ICP0

To countermeasure the host cellular intrinsic defense, cytomegalovirus (CMV) and herpes simplex viruses (HSV) have evolved the ability to disperse nuclear domain 10 (ND10, aka PML body). However, mechanisms underlying their action on ND10 differ. HSV infection produces ICP0, which degrades the ND10-...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Hou, Wangheng, Cruz-Cosme, Ruth, Wen, Fayuan, Ahn, Jin-Hyun, Reeves, Inez, Luo, Min-Hua, Tang, Qiyi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6232464/
https://ncbi.nlm.nih.gov/pubmed/30258013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01452-18
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