Two Polypyrimidine Tracts in Intron 4 of the Major Immediate Early Gene Are Critical for Gene Expression Switching from IE1 to IE2 and for Replication of Human Cytomegalovirus

The human cytomegalovirus (HCMV) major immediate early (MIE) gene is essential for viral replication. The most abundant products encoded by the MIE gene include IE1 and IE2. Genes of IE1 and IE2 share the MIE promoter (MIEP), the first 3 exons, and the first 2 introns. IE1 is expressed earlier than...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Virol
Κύριοι συγγραφείς: Hou, Wangheng, Torres, Lilith, Cruz-Cosme, Ruth, Arroyo, Fernando, Irizarry, Luis, Luciano, Dalia, Márquez, Arturo, Rivera, Leslie L., Sala, Antonio L., Luo, Min-hua, Tang, Qiyi
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2016
Θέματα:
Virus-Cell Interactions
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4984657/
https://ncbi.nlm.nih.gov/pubmed/27252533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00837-16
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