Two Polypyrimidine Tracts in Intron 4 of the Major Immediate Early Gene Are Critical for Gene Expression Switching from IE1 to IE2 and for Replication of Human Cytomegalovirus

The human cytomegalovirus (HCMV) major immediate early (MIE) gene is essential for viral replication. The most abundant products encoded by the MIE gene include IE1 and IE2. Genes of IE1 and IE2 share the MIE promoter (MIEP), the first 3 exons, and the first 2 introns. IE1 is expressed earlier than...

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Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: Hou, Wangheng, Torres, Lilith, Cruz-Cosme, Ruth, Arroyo, Fernando, Irizarry, Luis, Luciano, Dalia, Márquez, Arturo, Rivera, Leslie L., Sala, Antonio L., Luo, Min-hua, Tang, Qiyi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2016
Aiheet:
Virus-Cell Interactions
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4984657/
https://ncbi.nlm.nih.gov/pubmed/27252533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00837-16
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