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Pichia pastoris Exhibits High Viability and a Low Maintenance Energy Requirement at Near-Zero Specific Growth Rates

The yeast Pichia pastoris is a widely used host for recombinant protein production. Understanding its physiology at extremely low growth rates is a first step in the direction of decoupling product formation from cellular growth and therefore of biotechnological relevance. Retentostat cultivation is...

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Publicat a:Appl Environ Microbiol
Autors principals: Rebnegger, Corinna, Vos, Tim, Graf, Alexandra B., Valli, Minoska, Pronk, Jack T., Daran-Lapujade, Pascale, Mattanovich, Diethard
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4984280/
https://ncbi.nlm.nih.gov/pubmed/27208115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00638-16
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