Pichia pastoris regulates its gene-specific response to different carbon sources at the transcriptional, rather than the translational, level

BACKGROUND: The methylotrophic, Crabtree-negative yeast Pichia pastoris is widely used as a heterologous protein production host. Strong inducible promoters derived from methanol utilization genes or constitutive glycolytic promoters are typically used to drive gene expression. Notably, genes involv...

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Veröffentlicht in:BMC Genomics
Hauptverfasser: Prielhofer, Roland, Cartwright, Stephanie P, Graf, Alexandra B, Valli, Minoska, Bill, Roslyn M, Mattanovich, Diethard, Gasser, Brigitte
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4408588/
https://ncbi.nlm.nih.gov/pubmed/25887254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1393-8
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