In Pichia pastoris, growth rate regulates protein synthesis and secretion, mating and stress response

Protein production in yeasts is related to the specific growth rate μ. To elucidate on this correlation, we studied the transcriptome of Pichia pastoris at different specific growth rates by cultivating a strain secreting human serum albumin at μ = 0.015 to 0.15 h(–1) in glucose-limited chemostats....

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Bibliografske podrobnosti
Main Authors: Rebnegger, Corinna, Graf, Alexandra B, Valli, Minoska, Steiger, Matthias G, Gasser, Brigitte, Maurer, Michael, Mattanovich, Diethard
Format: Artigo
Jezik:Inglês
Izdano: WILEY-VCH Verlag 2014
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162992/
https://ncbi.nlm.nih.gov/pubmed/24323948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/biot.201300334
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