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Overexpression of the riboflavin biosynthetic pathway in Pichia pastoris

BACKGROUND: High cell density cultures of Pichia pastoris grown on methanol tend to develop yellow colored supernatants, attributed to the release of free flavins. The potential of P. pastoris for flavin overproduction is therefore given, but not pronounced when the yeast is grown on glucose. The ai...

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Détails bibliographiques
Auteurs principaux: Marx, Hans, Mattanovich, Diethard, Sauer, Michael
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517057/
https://ncbi.nlm.nih.gov/pubmed/18664246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-7-23
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