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Monitoring of transcriptional regulation in Pichia pastoris under protein production conditions
BACKGROUND: It has become evident that host cells react to recombinant protein production with a variety of metabolic and intrinsic stresses such as the unfolded protein response (UPR) pathway. Additionally, environmental conditions such as growth temperature may have a strong impact on cell physiol...
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主要な著者: | , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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BioMed Central
2007
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オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1919374/ https://ncbi.nlm.nih.gov/pubmed/17578563 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-8-179 |
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