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Canonical NF-κB signaling is uniquely required for the long-term persistence of functional mature B cells
Although canonical NF-κB signaling is crucial to generate a normal mature B-cell compartment, its role in the persistence of resting mature B cells is controversial. To resolve this conflict, we ablated NF-κB essential modulator (NEMO) and IκB kinase 2 (IKK2), two essential mediators of the canonica...
Αποθηκεύτηκε σε:
Τόπος έκδοσης: | Proc Natl Acad Sci U S A |
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Κύριοι συγγραφείς: | , , , , , , , , |
Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
National Academy of Sciences
2016
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4983837/ https://ncbi.nlm.nih.gov/pubmed/27099294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1604529113 |
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