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Tsc1 haploinsufficiency is sufficient to increase dendritic patterning and Filamin A levels
Most individuals with tuberous sclerosis complex (TSC) are born with a mutant allele of either TSC1 or TSC2 and a mosaic of psychological and cognitive defects. Tsc1 loss of heterozygosity contributes to severe dendritic abnormalities that are rescued by normalizing the levels of the actin-cross lin...
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| Publicado en: | Neurosci Lett |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4983256/ https://ncbi.nlm.nih.gov/pubmed/27345385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2016.06.037 |
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