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Tsc1 haploinsufficiency is sufficient to increase dendritic patterning and Filamin A levels
Most individuals with tuberous sclerosis complex (TSC) are born with a mutant allele of either TSC1 or TSC2 and a mosaic of psychological and cognitive defects. Tsc1 loss of heterozygosity contributes to severe dendritic abnormalities that are rescued by normalizing the levels of the actin-cross lin...
Gorde:
| Argitaratua izan da: | Neurosci Lett |
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| Egile Nagusiak: | , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2016
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4983256/ https://ncbi.nlm.nih.gov/pubmed/27345385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2016.06.037 |
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