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Tsc1 haploinsufficiency is sufficient to increase dendritic patterning and Filamin A levels

Most individuals with tuberous sclerosis complex (TSC) are born with a mutant allele of either TSC1 or TSC2 and a mosaic of psychological and cognitive defects. Tsc1 loss of heterozygosity contributes to severe dendritic abnormalities that are rescued by normalizing the levels of the actin-cross lin...

詳細記述

保存先:
書誌詳細
出版年:Neurosci Lett
主要な著者: Zhang, Longbo, Huang, Tianxiang, Bordey, Angélique
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4983256/
https://ncbi.nlm.nih.gov/pubmed/27345385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2016.06.037
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