Reduced Mitochondrial Membrane Potential Is a Late Adaptation of Trypanosoma brucei brucei to Isometamidium Preceded by Mutations in the γ Subunit of the F(1)F(o)-ATPase

BACKGROUND: Isometamidium is the main prophylactic drug used to prevent the infection of livestock with trypanosomes that cause Animal African Trypanosomiasis. As well as the animal infective trypanosome species, livestock can also harbor the closely related human infective subspecies T. b. gambiens...

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Detalles Bibliográficos
Publicado en:PLoS Negl Trop Dis
Main Authors: Eze, Anthonius A., Gould, Matthew K., Munday, Jane C., Tagoe, Daniel N. A., Stelmanis, Valters, Schnaufer, Achim, De Koning, Harry P.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982688/
https://ncbi.nlm.nih.gov/pubmed/27518185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004791
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