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ERAP1-ERAP2 dimers trim MHC I-bound precursor peptides; implications for understanding peptide editing
The processing of MHC class I antigenic precursor peptides by the endoplasmic reticulum aminopeptidase 1 (ERAP1) and ERAP2 is an important event in the cell biology of antigen presentation. To date, the molecular context by which the ERAP enzymes trim precursor peptides, and how ERAPs shape peptide...
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| Publicado en: | Sci Rep |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4981824/ https://ncbi.nlm.nih.gov/pubmed/27514473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28902 |
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