Lataa...

The ER aminopeptidase, ERAP1, trims precursors to lengths of MHC class I peptides by a “molecular ruler” mechanism

Endoplasmic reticulum aminopeptidase 1 (ERAP1) is an IFN-γ-induced aminopeptidase in the endoplasmic reticulum that trims longer precursors to the antigenic peptides presented on MHC class I molecules. We recently reported that purified ERAP1 trimmed N-extended precursors but spared peptides of 8-9...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Chang, Shih-Chung, Momburg, Frank, Bhutani, Nidhi, Goldberg, Alfred L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2005
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1287962/
https://ncbi.nlm.nih.gov/pubmed/16286653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500721102
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!