Antimicrobial Activity and Toxicity of the Major Lipopeptide Components of Polymyxin B and Colistin: Last-line Antibiotics against Multidrug-Resistant Gram-negative Bacteria

Polymyxin B and colistin are currently used as a ‘last-line’ treatment for multidrug-resistant Gram-negative bacteria. However very little is known about the pharmacological differences between polymyxin B(1), polymyxin B(2), colistin A, colistin B, the major cyclic lipopeptides components present i...

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Veröffentlicht in:ACS Infect Dis
Hauptverfasser: Roberts, Kade D., Azad, Mohammad A. K., Wang, Jiping, Horne, Andrew S, Thompson, Philip E., Nation, Roger L., Velkov, Tony, Li, Jian
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980087/
https://ncbi.nlm.nih.gov/pubmed/27525307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.5b00085
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