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Flow carbonylation of sterically hindered ortho-substituted iodoarenes
The flow synthesis of ortho-substituted carboxylic acids, using carbon monoxide gas, has been studied for a number of substrates. The optimised conditions make use of a simple catalyst system compromising of triphenylphosphine as the ligand and palladium acetate as the pre-catalyst. Carbon monoxide...
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| Published in: | Beilstein J Org Chem |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Beilstein-Institut
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4979912/ https://ncbi.nlm.nih.gov/pubmed/27559403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.12.147 |
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