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Flow carbonylation of sterically hindered ortho-substituted iodoarenes

The flow synthesis of ortho-substituted carboxylic acids, using carbon monoxide gas, has been studied for a number of substrates. The optimised conditions make use of a simple catalyst system compromising of triphenylphosphine as the ligand and palladium acetate as the pre-catalyst. Carbon monoxide...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Mallia, Carl J, Walter, Gary C, Baxendale, Ian R
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979912/
https://ncbi.nlm.nih.gov/pubmed/27559403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.12.147
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